Interfering with filovrirus replication

CDC/Dr. Fred Murphy; J. Nakano [Public domain] via Wikimedia Commons

Marburg virus, like its fellow filovirus Ebola virus, causes severe hemorrhagic fever with mortality rates reaching 90%. The Ebola virus outbreak currently sweeping western Africa has a mortality rate of 55–60%, according to the US Centers for Disease Control and Prevention. There are no approved treatments for viral hemorrhagic fever in humans; most infected individuals receive only supportive care. Now, scientists report a new strategy for treating Marburg virus using a tiny piece of RNA that interferes with its replication.

Lab Anim. (NY) 43, 336 (2014).
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