Common disinfectants impair reproduction in mice

Wellcome Images [creativecommons license] via Wikimedia Commons

Quaternary ammonium compounds (QACs) are disinfectants that were first introduced in the 1950s and are now commonly used in laboratory settings. They are generally considered safe, although their toxicity has never been rigorously evaluated. The lack of thorough toxicity testing of QACs recently came to light as two independent laboratories observed changes in the breeding performance of their mouse colonies.

Lab Anim. (NY) 43, 335 (2014).
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