A block that slows neurodegeneration

RicHard-59 [creativecommons license] via Wikimedia Commons

Results presented by Lynn Raymond (University of British Columbia, Vancouver, Canada) at the 2014 Canadian Neuroscience Meeting held 25–28 May in Montreal show that blocking specific glutamate receptors in the brain improved motor learning and coordination and prevented cell death in a mouse model of Huntington disease. Huntington disease can be detected before any clinical symptoms develop, providing a treatment window during which therapies that target early neuronal changes could be used to delay the onset of symptoms and slow neurodegeneration.

Lab Anim. 43, 224 (2014).
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