Small molecule, big advance against Marburg virus

F.A. Murphy, courtesy of the CDC

Marburg virus, like other filoviruses, causes hemorrhagic fever and has a fatality rate as high as 90%. Filoviruses are normally transmitted between individuals by blood or body fluids but are also infectious in aerosol form, which means they pose the risk of becoming a global health threat as well as being used as agents of biological warfare or terrorism. Given these possibilities, the lack of vaccines or therapies for filovirus infection is a great concern. Developing filovirus countermeasures is a top priority for the US Army Medical Research Institute of Infectious Diseases (USAMRIID; Fort Detrick, MD), said USAMRIID commander Col. Erin P. Edgar in a press release, and USAMRIID scientists recently reported new progress toward achieving that goal.

Lab Anim. (NY) 43, 154 (2014).
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