New models for studying hepatitis C

GrahamColm [creativecommons license] from Wikimedia Commons

For decades, chimpanzees have been the primary animal model for studying hepatitis C virus (HCV) infection. Efforts to develop other animal models have so far failed because chimps are the only species other than humans that are naturally susceptible to HCV. But as regulations surrounding chimpanzee research in the US have become more restrictive, the need for alternative models to test potential drugs and vaccines against HCV has become more urgent. Now, two independent research groups report advances in the development of new animal models for studying HCV, one rodent and the other primate.

Lab Anim. (NY) 42, 312 (2013).
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