Fishing for an antidote to cyanide

R. de Salis [creativecommons license] via Wikimedia Commons

The use of animals as sentinels for exposure to toxins is not new but has come a long way since the first canary was brought into a coal mine. A recent twist took the sentinel from airborne to aquatic, establishing three key results: first, zebrafish are a viable model for cyanide exposure in humans. Second, zebrafish provide an excellent medium for high-throughput chemical screening. And third, riboflavin can mitigate the harmful effects of cyanide toxicity in zebrafish.

Lab Anim. (NY) 42, 233 (2013).
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