Blocking inflammation to treat influenza

Cynthia Goldsmith / CDC [Public domain] via Wikimedia Commons

Influenza virus continually evolves, giving rise to both seasonal outbreaks and catastrophic pandemics. Current management strategies involve annual vaccines for prevention and compounds that block the viral surface protein neuraminidase for treatment. But annual vaccines are unlikely to be useful in the event of a pandemic infectious outbreak, and neuraminidase blockers must be taken very soon after infection in order to be effective, limiting their utility. Alternatives to these strategies are urgently needed.

Lab Anim. (NY) 42, 186 (2013).
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