Is caloric restriction a ‘fountain of youth’ for primates?
Paul Jean Gervais [Public domain] via Wikimedia Commons
Since European explorers first probed the New World’s resources, humans have sought a simple but universally effective defense against aging and death. Countless experiments have evaluated the life-extending effects of myriad molecules and manipulations, be they genetic or lifestyle, in animal models. When studies in species from flies to worms to rodents suggested that reduced caloric intake could lead to increased longevity, scientists fixed their attention on caloric restriction as a potential life-lengthener for humans.
Lab Anim. (NY) 41, 270 (2012).